alumis

Director Clinical Pharmacology & DMPK

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At a Glance

Location
South San Francisco
Experience
8+ years
Posted
2026-03-12T14:49:27-04:00

Key Requirements

Required Skills

Python

Domain Knowledge

  • Clinical
  • Insurance

Benefits & Perks

Time Off

phone stipend Unlimited PTO for Exempt employees Free ons

Health Insurance

r benefits include: Health insurance premiums paid at 90% for employee, 80%

Requirements

PhD, PharmD, or equivalent in Pharmacokinetics, Pharmacology, or related field.

6 to 8+ years of industry experience in Clinical Pharmacology, DMPK, or Quantitative Pharmacology.

Strong expertise in PK, PK/PD, DMPK, and translational sciences.

Proficiency with modeling/simulation platforms (NONMEM, WinNonlin, Simcyp, R, Python).

Excellent communication, organization, and ability to work independently in a fast-paced environment.

Alumis Inc. is an equal opportunity employer.

Responsibilities

Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs.

Conduct and interpret PK, PK/PD, exposure–response, and simulation analyses using tools such as NONMEM, WinNonlin, R, Python, and Simcyp.

Integrate translational and nonclinical PK/PD data to support FIH dose projections and DDI assessments.

Oversee bioanalytical CROs, ensuring high-quality PK/PD/biomarker data and GLP/GCP compliance.

Partner with Clinical Operations on sample management and protocol design.

Communicate quantitative findings clearly and contribute to regulatory documents (protocols, IBs, INDs, NDAs, IMPDs).