Director, Business & Operations – US Commercial

10+ years of progressive experience in commercialization strategy, commercial operations, program management, or related roles within biotechnology or pharmaceuticals, or relevant experience from a biotech or life sciences consulting firm focused on commercialization or commercial planning.

Experience supporting senior leaders and leadership teams in high‑growth or launch‑stage environments.

Demonstrated experience with budget management, financial planning, and vendor/contract oversight.

High integrity and discretion in handling sensitive and confidential information.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

The Director, Business & Operations – US Affiliate will serve as a key strategic and operational partner to the SVP, Head of US Affiliate, supporting the effectiveness, execution, and scalability of the US Affiliate organization.

This role will provide operational leadership and continuity across the function, enabling the SVP and US Affiliate Leadership Team to remain focused on the highest‑impact priorities as Dyne builds and grows its US presence.

The Director will be responsible for business operations across the US Affiliate, including budget ownership and financial planning, vendor and contract management, operating rhythm and governance, and the execution of function‑wide initiatives.

Acting as a connective hub across Commercial, Medical, Finance, Legal, HR, and other G&A partners, this leader will translate strategic priorities into well‑structured plans, drive execution, and ensure visibility into progress, risks, and resource needs.

Strategic & Operational Partnership

Serve as a trusted thought partner to the SVP, Head of US Affiliate, helping translate affiliate strategy and priorities into clear, actionable, and measurable operating plans.