VP/Senior Director, Clinical Operations

History of orchestrating clinical trials through CRO partners with accountability for operational delivery

Recent experience managing first-in-human trials

Quantitative mindset — you track metrics, report numbers rather than anecdotes, and drive for measurable improvements quarter-over-quarter

Experience managing clinical trial budgets, forecasts, and resource planning

Experience managing trials in metabolic disease and hepatology

History of developing nucleic acid medicines (mRNA, ASO, siRNA) and lipid nanoparticle (LNP)-vectored products

NewLimit offers generous benefits to ensure our team can focus on our mission:

Health, dental, and vision insurance

401(k) with company match

Paid parental leave

Industry-leading paid time off (PTO) — 20 days/year for all employees + holidays

Meals and snacks on-site

Lead clinical trial execution through protocol development, CRO selection and management, and startup activities across several geographies (US, AUS/NZ, EU, UK)

Collaborate with clinical development to ensure trial designs and execution provide maximum benefit to patients and maximum information per dollar

Manage and own company-wide clinical trial timelines and budgets, construct and instrument clinical operations metrics

Disentangle the inevitable operational challenges that arise in trial execution — debugging recruitment, cross-border logistics, regulatory compliance, and staffing

Build and manage a bar-raising clinical operations team as the founding member

Support regulatory submissions and ongoing global compliance obligations