Research Scientist - Protein Sciences

Foundational hands-on experience in recombinant protein expression and purification, typically gained through academic research (0-2 years).

Demonstrated expertise in common protein expression/purification techniques and a strong aptitude for independent experimental design and troubleshooting.

Familiarity with preparing and characterizing proteins specifically for X-ray crystallography or Cryo-EM.

Direct experience with challenging targets such as membrane proteins (e.g., GPCRs, ion channels).

Working knowledge of protein refolding methods from inclusion bodies.

Experience in generating and evaluating stable cell lines for protein expression.

We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:

Multiple relocation packages

Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)

8-week parental leave

9 Employee Resource Groups

Annual bonus offering

As a Research Scientist on our Antibody Discovery team, you will play a critical role in advancing Elanco's pipeline by producing high-quality proteins essential for groundbreaking structural biology studies.

In this lab-based role, you will lead protein production for parasitology, small molecule, and large molecule projects, tackling complex expression challenges and mastering automated purification systems.

This is an exciting opportunity to directly contribute to the discovery of novel animal health solutions.

Design and execute multi-platform protein expression and purification strategies (bacterial, insect, mammalian) for structural biology studies.

Develop, optimize, and troubleshoot protocols for automated chromatography (AKTA) and various purification techniques, including Affinity (NiNTA, GST), Ion Exchange (IEX), and Size Exclusion Chromatography (SEC).

Employ advanced genetic construct design (e.g., tag selection, truncation screening, codon optimization) to enhance protein solubility and suitability for structural biology studies.