Scientist, Solid Tumor CAR-T

Primary human T cell isolation, activation, lentiviral transduction, and expansion is required.

Multicolor flow cytometry: panel design, data acquisition (e.g., Attune,Novocyte, Cytek Aurora), and analysis (FlowJo).

Standard molecular biology: PCR/qPCR, lentiviral vector packaging and titration, Western blot.

Familiarity with Incucyte, MSD, LDH release assay.

Contributions to innovation in cell therapy (publications, patents, or conference presentations).

$110,706

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$145,303 USD

Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

Work Authorization & Employment Eligibility

Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.

This role is central to our in vivo CAR-T platform and will drive preclinical development from construct design through animal model efficacy studies.

Design and execute in vitro functional assays.

Perform Binder selection for CAR design.

Handling and engineering human and murine T cells.

Engineering and maintaining various cancer cell lines for model development.

Analyze and interpret data, troubleshooting, present to and engage internal stakeholders

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