Team Leader, Medicinal Drug Design, London

Essential:

PhD in Medicinal Chemistry, Synthetic Organic Chemistry, or a related technical field, or equivalent industrial experience.

8+ years’ professional experience in a Medicinal Chemistry role, operating within a biotech, pharma or CRO setting.

Proven track record of leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation/candidate nomination), with familiarity of optimisation of DMPK.

Experience of contributing to structure-based drug design problems.

Experience of leading a high-performing scientific team, mentoring and empowering them to thrive in their roles.

You will be responsible for line managing and mentoring a small team of talented and high-performing Medicinal Chemists, fostering their scientific growth and career development. Additionally, you will provide scientific leadership and strategic direction for key drug discovery projects, guiding them from initiation towards clinical candidate selection. Working alongside world-leading AI/ML scientists, you will play a critical role in driving project success, enhancing our AI platform through your technical expertise.

If you are a skilled Medicinal Chemist with leadership experience and a passion for applying cutting-edge technology to complex scientific challenges, this role offers an unparalleled opportunity for impact and growth.

Provide line management for a team of 2-4 Medicinal Chemists. Set clear goals, provide regular feedback, support their professional development, and foster a collaborative and high-performance team environment.

Invent new medicines. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either a Medicinal Chemistry Lead or overall Project Lead.

Collaborate cross-functionally to support the data-driven delivery of high quality scientific solutions to complex technical problems.

We are a dynamic team of Medicinal Chemists transforming how drugs are designed. By partnering deeply with our AI/ML colleagues, we are doing more than just leveraging the Isomorphic Labs drug design engine - we are actively shaping it. We use our domain expertise to challenge and refine our algorithms, creating a powerful symbiotic relationship that drives our internal and collaborative portfolios. Our team closely together in a supportive environment, where everyone is valued for their medicinal chemistry expertise and experience they bring to the group. We have a strong growth mindset and prioritise continued development and learning.

We are looking for a Team Leader, Medicinal Drug Design to champion this cross-disciplinary approach, fostering a supportive team culture where continuous learning and the adoption of next-generation tools are the standard, not the exception. This is a pivotal role for an experienced and motivated scientific leader eager to shape the future of drug discovery at the intersection of medicinal chemistry and artificial intelligence.