Principal Scientist - Toxicology

AbCellera’s hiring range for this role is CAD $151,420 - $190,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.

That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them.

You will be responsible for designing, planning, monitoring, and reporting of non-GLP and GLP toxicology studies and provide nonclinical safety support for early to late stage programs.

Leading the planning, design, execution and interpretation of nonclinical toxicology programs in support of IND, CTA and BLA submissions, including general toxicity and reproductive and developmental toxicology studies, in alignment with global regulatory expectations and program strategy

Serving as the primary scientific interface with contract research organizations (CROs), providing strategic oversight during protocol development, study conduct, data interpretation, and report finalization to ensure timely, high-quality, and GLP-compliant delivery of nonclinical studies

Providing critical scientific assessment of toxicology data and communicating clear, actionable risk-benefit evaluations and recommendations to project teams and senior leadership, including potential implications for clinical development and regulatory strategy

Driving the development and evolution of integrated nonclinical safety strategies across AbCellera’s therapeutic portfolio, ensuring consistency, scientific rigor, and alignment with company objectives

Creating medicines is the most important work we can do.

We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline.

Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug (IND)-enabling activities, and more than 20 active discovery programs across multiple modalities and indications.

We believe that when tenacious people share a vision and work together, they can truly have a positive impact. That’s why we hire for character and intelligence, not just for CVs or experience.

We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.

To apply