beamtherapeutics

Senior Scientist, LNP Sciences

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At a Glance

Location
Cambridge, Massachusetts, United States
Experience
4+ years
Posted
2026-03-09T17:23:05-04:00

Key Requirements

Domain Knowledge

  • Education
  • Engineering
  • Pharmaceutical

Requirements

PhD or MS in Pharmaceutical Sciences, Chemical Engineering, Bioengineering or related field with drug product and CMC development experience (PhD 4+ years or MS 12+ years).

Deep understanding of sterile product development. Prior industry research experience, especially in nucleic acids and drug delivery, is required. Experience with development of antibody-drug conjugates and/or biologics is preferred.

Knowledge of statistical techniques and concepts (regression, properties of distributions, statistical tests, and proper usage, etc.).

Ability to adapt to increasing scope and complexity of work brought on by growth/change and help others manage through change.

A successful candidate will have excellent computational, written, and verbal communication skills, strong organizational abilities, and an ability to work with a diverse group of scientists and engineers.

Ability to work in a hybrid environment with sufficient on-site presence.

Responsibilities

Beam is seeking a scientist with expertise in formulation and ligand conjugation. The candidate will work on formulation, ligand conjugation, and scale-up of lipid nanoparticles (LNPs) targeting different organs and cell types. They will work as part of a team to develop drug products with the goal of bringing in vivo base editing to patients.

We are looking for an ambitious candidate who wants to grow within the LNP Sciences group. This candidate will help shape the LNP platform and grow with the aspirations of the organization as we advance into later stages of development.

Responsible for formulation design, development, characterization, and technology transfer to enable development of Beam sterile drug products.

Accountable as an individual contributor to support formulation development as well as providing necessary guidance and support of drug product control strategy for drug candidates across all stages of development.

Independently design, execute, analyze, and document experiments to optimize LNP potency, tolerability, biodistribution, and ligand conjugation.