Translational IHC (Consultant)

5+ years of experience in Translational biomarker development; IHC/mIF assay development in oncology and immunology.

Deep understanding of TME, Immune cell phenotyping.

Experience supporting clinical trials.

Proficiency in image analysis platforms such as HALO, VisioPharm, QuPath, etc.

This role bridges pathology, biomarker and clinical development, ensuring high-quality tissue biomarker data generation to inform baseline, compound MoA, target engagement and safety.

Collaborate with selected CRO to develop, optimize and validate chromogenic IHC, mIF and spatial Omics as well as ensure assays are phase-appropriate and fit-for-purpose (exploratory to clinical and potential CDx pathway).

Define technical requirement and quality criteria such as antibody selection and qualification, benchmark and scoring algorithms and support GCP-aligned assay validation whenever applicable.

Review study design, validation and analysis reports.

Partner with TR scientists, clinical development and pathologists to translate biological questions and clinical challenges into quantitative image-based endpoints and computational workflows.

Interpret data in collaboration with Translational scientists and pathologists.

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