newlimit
Senior Research Associate, PK/PD Assays
At a Glance
- Location
- South San Francisco
- Experience
- 2+ years
- Compensation
- eals and snacks Salary Range: $90,000 to $110,000. Compensation for the role wi
- Posted
- 2026-03-20T15:46:59-04:00
Key Requirements
Domain Knowledge
- Regulatory
Benefits & Perks
Health, Dental, and Vision insurance 401(k) plan with company match Paid par
Requirements
2+ years of laboratory experience in molecular biology and quantitative assay development (e.g., qPCR, RT-qPCR, ddPCR, ELISA, NGS-based)
Hands-on experience with primary cell culture, tissue harvesting and complex biological matrices for molecular assays
Familiarity with bioanalytical assay qualification/validation principles for PK/PD biomarker measurements
Understanding of data quality, documentation, and experimental practices aligned with preclinical regulatory expectations (e.g., GLP-like practices or bioanalytical method validation guidelines)
Experience working in environments following GLP or regulated bioanalytical workflows supporting preclinical or IND-enabling studies
Experience with flow cytometry sorting
Compensation & Benefits
NewLimit provides generous benefits so our team can remain focused on our mission:
Comprehensive Health, Dental, and Vision insurance
401(k) plan with company match
Paid parental leave
Industry-leading PTO: 20 days per year plus holidays
On-site meals and snacks
Responsibilities
Develop, validate, and execute PK and PD biomarker assays to support preclinical studies and therapeutic discovery programs
Design and perform molecular biology assays (e.g., qPCR, RT-qPCR, ddPCR, NGS-based assays, ELISA) to quantify nucleic acids, gene and protein expression in biological samples
Contribute to experimental sample processing and preparation workflows including animal dissections, tissue harvesting, and primary cell culture
Perform state-of-the-art single cell profiling experiments to map epigenetic features of aging
About the Company
NewLimit is seeking a Senior Research Associate with strong experience in molecular biology and translational biomarker assay development to join our team. This role will contribute to the development and execution of pharmacokinetic (PK) and pharmacodynamic (PD) assays to support our therapeutic programs. You will work closely with cross-functional teams to develop and implement molecular assays that quantify the biodistribution of our mRNA-LNP medicines and the biological response to them in preclinical studies.