Research Associate, Translational Biology (CONTRACT)

At least 2 years direct full-time experience with in vivo studies in academia or the biotechnology and pharmaceutical industries

Experience working in vivarium laboratory settings with rats

Demonstrated ability to be hands on and work directly with rodent models, including multiple routes of administration (e.g.

oral, subcutaneous, intraperitoneal, intravenous, intramuscular) and sample collection (e.g.

tail vein bleeds, jugular bleeds, cardiac puncture, necropsies, etc.).

Experience working with other scientists to collect and record study data consistently and accurately

The Veterinary Technician / Research Associate will initially be responsible for conducting in vivo rodent studies, with the potential to engage in additional ex vivo or in vitro studies in the Translational Sciences Department to support the advancement of Septerna’s small molecule drug discovery pipeline.

The candidate will work independently and collaboratively in an inter-disciplinary setting to execute experiments in preclinical models to understand in vivo pharmacology, establish PK/PD relationships, and inform the efficacy of Septerna’s therapeutic candidates.  They will help generate in vivo and/or ex vivo data to determine therapeutic mechanisms of action, in vivo efficacy, and rank candidates for preclinical development.  This role is expected to be primarily in the lab with some desk work.

We are committed to the development of meaningful therapeutics for patients with indications of high unmet need.

This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development.  You will help move therapies through preclinical development, positioning them for success in the clinic.  The successful candidate will add their passion, unique talents, and expertise to a dynamic team on the frontlines of innovative therapeutic development.

Execute in vivo pharmacology studies to understand therapeutic mechanisms in relevant disease models

Work collaboratively to determine the mechanism of action of drug candidates, primarily with in vivo models