vaxcyte
Scientist II, Conjugation Development
At a Glance
- Location
- San Carlos, California, United States
- Experience
- 2+ years
- Compensation
- uity component. Salary Range: $146,000 - $170,000 (SF Bay Area). We are an equa
- Posted
- 2026-03-06T20:14:00-05:00
Benefits & Perks
titive and includes comprehensive benefits and an equity component. $146,000 - $1
Requirements
• PhD in chemistry, biochemistry, or related field with minimum 2 years of industry experience, or combination of industry and postdoctoral research; MS with minimum 7 years industry experience, or BS with minimum 10 years of experience industry.
• Strong biochemistry and organic chemistry knowledge base underpinning several years’ experience preparing bioconjugates.
• Proficiency with small- and large-scale techniques for purification of bioconjugates, including tangential flow filtration.
• Proficiency in a variety of techniques for bioconjugate analysis such as colorimetric assays, HPLC, and SEC-MALS.
• Sufficient knowledge of analytical principles to develop fit-for-purpose analytical methods as needed and provide cross-functional feedback on draft analytical methods.
• Experience with Design of Experiments is desirable.
Compensation & Benefits
The compensation package will be competitive and includes comprehensive benefits and an equity component.
$146,000 - $170,000 (SF Bay Area).
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
Responsibilities
• Optimize and troubleshoot multi-step syntheses of protein-polysaccharide conjugates.
• Purify polysaccharides and conjugates using a variety of methods including dialysis, size-exclusion chromatography, and tangential flow filtration (TFF).
• Analyze polysaccharides and conjugates with a variety of analytical methods. Develop new laboratory workflows and analyses beyond established procedures when appropriate.
• Advise team members on experimental design, interpretation of results, and troubleshooting.
• Model and train team members on best practices for adherence to protocols and data management.
• Serve as a subject matter expert during tech transfer of conjugation processes to contract manufacturing organizations.