Chemistry Lead

5+ years hands-on analytical chemistry experience, with 2+ years in supervisory or laboratory management role.

Demonstrated expertise in multiple analytical techniques: spectroscopy (FTIR, Raman, NMR, UV-Vis), chromatography (GC, HPLC, IC), thermal analysis (DSC, TGA), mass spectrometry, XRD, or elemental analysis.

Experience developing analytical methods, writing SOPs, implementing quality control programs, and maintaining laboratory compliance in regulated environments.

Strong knowledge of laboratory instrumentation operation, maintenance, troubleshooting, and calibration.

Proven ability to interpret complex data, solve technical problems, and communicate results clearly to diverse audiences.

Commitment to laboratory safety culture and experience with chemical hygiene plans, hazardous material handling, and emergency response procedures.

The base salary range for this role is

$160,000-$200,000

annually.

Compensation bands are determined by role, level, location, and alignment with market data. Individual level and base pay is determined on a case-by-case basis and may vary based on job-related skills, education, experience, technical capabilities and internal equity.

Please note that the stated salary range is an estimate and may be adjusted based on market conditions, business needs, or other factors.

In addition to base salary, for full-time hires, you may also be eligible for long-term incentives, in the form of stock options, and access to medical, vision & dental coverage as well as access to a 401(k) retirement plan.

As Chemistry Lead at General Matter, you'll build and lead the analytical chemistry capabilities that enable our advanced uranium enrichment operations from the ground up. You'll establish laboratory methods, quality systems, and team processes that directly support production operations, NRC compliance, and nuclear material accountability.

This is a rare opportunity to shape chemistry operations at a next-generation nuclear facility during rapid commercial scale-up, where your technical decisions immediately impact our ability to strengthen domestic nuclear fuel supply.

Oversee materials testing activities to support project and operational needs

Develop, validate, and implement analytical methods for material characterization and quality control; establish SOPs for testing protocols, sample handling, data documentation, and reporting standards.

Ensure laboratory compliance with quality assurance requirements, safety protocols, and regulatory expectations; implement quality control procedures including method validation, measurement uncertainty analysis, and audit readiness.

Manage laboratory operations including equipment maintenance, calibration, inventory management, sample queue prioritization, and vendor coordination.

General Matter is enriching uranium in America.

Our goal is to design, build, and operate the world’s lowest-cost enrichment services in the United States.

Our mission is to restore America’s ability to produce nuclear fuel—fuel that will power AI, advanced manufacturing, critical industries, and the next generation of nuclear reactors.

Ultimately, our work will help power national ambitions and enable a high-energy society.

We were incubated by Founders Fund, like Anduril and Palantir before us, and are backed by top-tier investors. Our lean, world-class team of engineers and operators is applying a first-principles approach to solving the problem of nuclear fuel production.

We are a mission-driven company with a culture of urgency, accountability, and transparency.