Director, Clinical Development

Contribute to building scalable Clinical Sciences processes and capabilities.

10+ years of experience in Clinical Sciences, Clinical Development, or a related function within the biopharmaceutical industry.

Demonstrated experience supporting or leading early-phase clinical trials (Phase 1/2), including protocol development and data interpretation.

Strong understanding of clinical drug development, including study design, endpoints, and regulatory considerations.

High attention to detail and commitment to data quality and scientific rigor.

Septerna is seeking an experienced and highly motivated Director of Clinical Sciences to provide scientific and operational leadership across our early clinical development programs.

This individual will play a critical role in the design, execution, and interpretation of clinical studies, working cross-functionally to ensure high-quality, decision-ready data that advances our pipeline.

This position will work closely with Clinical Development, Clinical Operations, Regulatory, Early Development, Biometrics, and Program Management functions and will report to the Senior Medical Director, Clinical Development.

Lead the design, planning, and execution of early-phase clinical trials (Phase 1 and Phase 2), including protocol development and study-related documents.

Drive development of key study documents including protocols, investigator brochures, clinical study reports (CSRs), and informed consent forms.

Collaborate with Clinical Operations to ensure effective study execution, including site selection, enrollment strategies, and timeline management.