Scientist - Tech Transfer

PhD in Molecular Biology, Biochemistry, or related field; or Master’s with 2–5+ years of industry experience; or Bachelor’s with 5+ years of relevant experience

Strong foundation in molecular biology techniques, including DNA/RNA purification, PCR/qPCR, and molecular cloning

Hands-on experience developing and optimizing mammalian cell culture systems for protein expression (e.g., HEK, CHO)

Experience designing expression constructs and optimizing systems for yield, solubility, and activity across host platforms

Proven ability to develop and optimize upstream and downstream workflows, including transfection and protein purification strategies

Demonstrated experience in experimental design, data analysis, troubleshooting, and method development in complex biological systems

We are seeking a

Scientist

to join our Tech Transfer team, focused on advancing and scaling synthetic biology workflows across DNA-based and mammalian cell culture systems. This role sits at the interface of R&D and production, where you will drive the successful transfer of new products and processes into high-throughput manufacturing environments.

You will play a key role in developing, optimizing, and troubleshooting workflows spanning molecular biology and mammalian cell culture systems, ensuring processes are robust, scalable, and production-ready. This includes hands-on experimental work, cross-functional collaboration, and enabling operational teams through training, technical guidance, and documentation.

This is a highly collaborative role partnering with teams across operations, automation engineering, and bioinformatics to translate innovation into reliable production processes. A key component of this work will be designing processes with automation in mind, enabling deployment across a diverse suite of liquid handling platforms to support scalable and standardized manufacturing.

We are looking for someone who combines strong experimental rigor with practical problem-solving, and who is equally comfortable working at the bench and thinking strategically about process improvement. Experience across both DNA technologies (e.g., NGS, cloning) and mammalian cell culture/protein expression systems is highly valued.

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we serve people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals, and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this Oregon-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.