FirstPrinciples

Biotech & Pharma · Software

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FirstPrinciples is building AI to accelerate scientific discovery. Our core product is the Theo Platform, a research environment built to help researchers iterate faster, validate rigorously, and reach verified results they can trust. We're a fast-growing, remote-first team of builders, researchers, engineers, and thinkers working across Canada, the US, the UK, and expanding globally. What brings us together is a shared curiosity about how the universe works, and a belief that we can build systems that help us explore it more effectively. We spend our time working on questions that don't have clear answers, like how to design AI that can reason through scientific problems, and how the scientific process as a whole might evolve. This is work that sits somewhere between creativity and rigorous thinking, and often requires comfort with ambiguity and iteration. If you're someone who enjoys tackling big, abstract problems and exploring ideas that don't yet have a defined path forward, you'l

Founded
2024
Headquarters
Toronto, Ontario, CA

Hiring activity

Open roles
1
Posted in the last 30 days
1
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What FirstPrinciples says about its culture

Achievement — work you can point at and feel proud ofwork you can point at and feel proud ofAchievementIndependence — room to make your own decisionsroom to make your own decisionsIndependenceRecognition — getting somewhere, and being recognized for itgetting somewhere, and being recognized for itRecognitionRelationships — colleagues you get on with, and work that helps peoplecolleagues you get on with, and work that helps peopleRelationshipsSupport — managers who back their people upmanagers who back their people upSupportWorking conditions — steady, well-run conditions you can rely onsteady, well-run conditions you can rely onWorkingconditions

What FirstPrinciples says it offers, drawn from its own website.

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Our mission is to understand the nature of reality by advancing AI-driven discovery in fundamental science.

  • Reasoning from first principles

    “We reason from the ground up. Rather than relying on convention, we break problems down and build from first principles.”Source

  • Long-term thinking

    “Scientific research is a long-term endeavour. We build with that horizon in mind, prioritizing systems that can support researchers as methods and technologies evolve.”Source

  • Builder mentality

    “We’re all builders. We move quickly, test ideas early, and focus on creating systems, tools, and technology that make discovery possible.”Source

  • Urgency toward a time-bound moonshot

    “Our moonshot is time-bound. We move with urgency and purpose, knowing every step counts toward achieving our goal.”Source

They say people do well here who…

  • World class talent thrives here
  • Deeply curious, highly capable, genuinely invested
  • Entrepreneurial mindset, initiative and creativity
  • Autonomy and self-direction in remote work

Quoted from FirstPrinciples's own website. TeaKo does not verify these claims.

Latest openings

1 open role at FirstPrinciples. Members see each one.